The live-action Powerpuff Girls show on the CW is a go and the three leads have just been cast. I was never into the cartoon, but I think this concept actually seems like it just might work!
Dove Cameron (Descendants), Chloe Bennet (Agents of SHIELD), and Broadway’s Yana Perrault will play the popular superheroes. In the context of this series, the trio are now adults but remain resentful that they didn’t have a childhood because they were too busy being superheroes. The show has been ordered for a pilot written by Oscar winner Diablo Cody and Heather Regnier (Veronica Mars, Sleepy Hollow). CW guru Greg Berlanti is among the executive producers.
As for which actress is playing which Powerpuff Girl: Cameron is Bubbles, Bennet is Blossom, and Perrault is Buttercup, according to the Hollywood Reporter.